Kutariswa kwepamhepo kunovimbisa kuti iyo substrate yemukati iri pazasi pechikumbaridzo, kuve nechokwadi chebiological enzyme chiitiko mukati mekuita, uye nekuwedzera iyo hydrolysis reaction rate.
Amide makomisheni akakosha organic synthesis yepakati uye makemikari uye anoshandiswa zvakanyanya mukurapa, mishonga yekuuraya zvipembenene, chikafu, kuchengetedza kwezvakatipoteredza, kugadzira mafuta uye mamwe minda.Iyo hydrolysis reaction yeboka renitrile muboka reamide ndiyo imwe yenzira dzakakosha dzekugadzira amide komisheni muindasitiri.
Iyo biocatalyst inoshandiswa mune yakasvibira synthesis process yeimwe amide komboni, uye basa rayo rinokanganiswa zvakanyanya nekusangana kwe substrate uye chigadzirwa muhurongwa.Kana iyo substrate concentration yakanyanyisa, iyo catalyst ichavharwa nyore nyore, zvichiita kuti zvisakwanise kuenderera mberi nekuita synthesis;kana iko kusungirirwa kwechigadzirwa kwakanyanyisa, kunotungamira mukuunganidzwa kwe substrate uye yakaderera synthesis kunyatsoshanda.Kuti uve nechokwadi chekuita kwakaringana kwebiological enzyme catalysts mune synthesis maitiro, inoshanda tekinoroji nzira dzinodiwa kuti utarise uye mhinduro inogadzirisa kutarisisa kwenitrile substrates uye amide zvigadzirwa munguva chaiyo panguva yekuita maitiro.
Parizvino, nzira dzakaita sesampling panguva dzakatarwa uye kuita gasi chromatography-mass spectrometry mushure memuenzaniso pre-kurapa inowanzo shandiswa kuona iyo substrate uye zvigadzirwa zvemukati mune reaction system.Offline yekuona mhedzisiro inononoka, mamiriro ekuita aripo haakwanise kuzivikanwa munguva chaiyo, uye zvakaoma kuita kudzora mhinduro uye kugadzirisa kwe substrate yemukati, uye mukana wekudya wakanaka unogona kupotsa.Online spectral yekuongorora tekinoroji ine zvakanakira kukurumidza kuona kumhanya uye hapana chikonzero chemuenzaniso pretreatment.Iyo inogona kuona nekukurumidza, chaiyo-nguva, in-situ uye nehungwaru ongororo yemaitiro system, uye ine yakasarudzika mabhenefiti mune yakasvibira synthesis yeamide makomisheni.
Mufananidzo uri pamusoro unoratidza kuongororwa kwepamhepo kwemaitiro ekugadzira acrylamide kuburikidza ne bioenzymatic reaction yeimwe nitrile compound.Kubva 0 kusvika t1 mushure mekuita kwatanga, chiyero chekudyisa chenitrile mbishi zvinhu zvakakura, uye mwero wekuunganidza wezvose zviri zviviri substrate nechigadzirwa unokurumidza.Pa t1, iyo substrate yemukati iri padyo nepamusoro pemuganho wechikumbaridzo.Panguva ino, vashandi vekugadzira vanodzikisa chiyero chekudyisa chemidziyo kuchengetedza iyo substrate yekumisikidza mune yekuita system mukati meiyo inodzoreka renji, uye chigadzirwa chinogona kuramba kuunganidza nekukurumidza.Chekupedzisira, kana kuita kwacho kuchienda kunguva t2, zvirimo zvechigadzirwa zvinoungana kusvika padanho rakatarwa, uye vashandi vekugadzira vanomira kuwedzera nitrile mbishi zvinhu.Mushure meizvozvo, iyo substrate level inosvika zero uye izvo zvechigadzirwa zvakare zvinogara zvakagadzikana.Munguva yese yekuenderera mberi kwekugadzira maitiro, kutarisa pamhepo kunovimbisa kuti biological enzyme catalytic reaction inoenderera nemazvo.
Mune yakakura-chiyero synthesis, online yekutarisa tekinoroji inonyanya kukosha.Ruzivo rwechokwadi-nguva ye substrate uye kutariswa kwechigadzirwa kunogona kubatsira mhinduro kugadzirisa iyo substrate yemukati mukati meiyo inonzwisisika renji.Munguva yekuita maitiro, inogona kukwidziridza chiitiko cheiyo biological enzyme catalyst, kuvandudza kushanda kweiyo synthesis reaction, uye kubatsira kudzora maitiro maparamita mune yakakwana mamiriro.Wedzera hupenyu hwesevhisi yebiological enzyme catalysts uye wedzera mabhenefiti.
Nguva yekutumira: Jan-23-2024